Neuroscience

Cambridge has a strong tradition in neuroscience. We have hosted the first analysis of neural signalling in the 1930s with Bryan Matthews and Lord Edgar Adrian; identified the mechanisms that generate action potential in the 1950s with Alan Hodgkin and Andrew Huxley; and elaborated some of the first theoretical approaches to function in brain circuits since the 1960s. Neuroscience at Cambridge continues to grow and to incorporate new ideas and approaches into diverse research interests.

We have a strong research representation at cellular and molecular level, with groups working on synaptic transmission, local network properties and plasticity in local neural circuits, aspects of molecular signalling and transduction of sensory stimulus. Our developmental neurobiologists are also tackling problems associated with how a brain is built.

At neural systems level, we are working onhow sensory systems are able to process and represent information. We are studying the sense of hearing in mammals, auditory analysis, visual processing of information and predation. We are also interested in how the motor systems and neuroendocrine systems function.

At the level of behaviour, we have groups working on aspects of motivation and cognition, like how rewards are preceived and processed in the brain and how emotions can affect or disrupt decision making.

Labs

	Adams lab Visualising morphogenetic mechanisms		Baker lab Neurogenic placodes and the neural crest: development of the vertebrate peripheral sensory nervous system
beltramo	Beltramo lab How the brain transforms sensory signals into the neural representations of the outside world that guide our behaviour		Brand lab Stem cells to synapses: regulation of self-renewal and differentiation in the nervous system
	Bray lab Neural and epidermal development in Drosophila: from signalling to morphogenesis		Buckley lab Optogenetically probing cell polarity and brain development
	Cahill lab Neurochemical and molecular mechanisms underlying memory		Cardona lab Neural circuit reconstruction of Drosophila larva
	Clarke lab Neural and neurochemical basis of negative emotional behaviour and their implications for psychiatric disorders		Edgley lab How information is processed in motor systems
	Fleming lab Zebrafish models of neurodegeneration to investigate how protein clearance pathways affect disease severity		Franze lab Mechanics in nervous system development and pathology
	Galliano lab Neural network development, plasticity and impact on behaviour		Herbison lab Properties and functioning of the key neural populations controlling fertility in mammals
	Holt lab Axon guidance in the developing brain		Jones lab How neuronal communication is disrupted in pathological states that mimic neurological disorders
rabies_host_cells_100.jpg	Keshavarzi lab Neural mechanisms underlying the sense of self-motion and spatial orientation
krupic.png	Krupic lab Underlying mechanisms of the brain GPS system		Mason lab Structure, function and evolution of the vertebrate ear
	Matthews lab Phototransduction and olfactory transduction		Mierau lab Synaptic and network function in cortical development and neurodevelopmental disorders
	Parker lab Neuronal networks and plasticity after recovery from spinal cord injury		Paulsen lab Cellular basis of information processing in the mammalian brain
	Poort lab Neural mechanisms of visually-guided learning, attention and decision-making	raffa.png	Raffan lab Underlyng links between genes and obesity in dogs and humans
	Roberts lab Neural circuits underlying the regulation and dysregulation of positive and negative emotion		Robinson lab Ion channels and neuron dynamics
	Schultz lab Reward processing and economic decisions in the brain	coverimage.jpg	Tamura lab Circuit physiology of cognition
	Winter lab Primitive neural mechanisms of auditory scene analysis