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Fat fetuses: thyroid hormone deficiency before birth modifies adipose tissue development

Fat fetuses: thyroid hormone deficiency before birth modifies adipose tissue development

New study by PDN and collaborators demonstrates that thyroid hormone deficiency before birth causes overgrowth of white adipose tissue

Fat fetuses: thyroid hormone deficiency before birth modifies adipose tissue development - Read More…

Study reveals novel aspects of the human metabolic response to hypoxia

Study reveals novel aspects of the human metabolic response to hypoxia

In a report published in the New England Journal of Medicine, Dr Andrew Murray and Dr Katie O’Brien of PDN, along with an international team of collaborators, describe new aspects of the human metabolic response to low oxygen levels

Study reveals novel aspects of the human metabolic response to hypoxia - Read More…

Cancer prediction through artificial neural network algorithms

Cancer prediction through artificial neural network algorithms

International team of researchers led by Paul Schofield developes a new algorithmic method capable of analyzing molecular data collected in studies and identifying genetic patterns associated to the development of cancer

Cancer prediction through artificial neural network algorithms - Read More…

New study by Ewa Paluch's lab makes cover of Developmental Cell

New study by Ewa Paluch's lab makes cover of Developmental Cell

The researchers used proteomics to identify key factors controlling actin organisation in mitosis

New study by Ewa Paluch's lab makes cover of Developmental Cell - Read More…

Common technique used in IVF impacts placenta growth and function

Common technique used in IVF impacts placenta growth and function

New mouse study by the Watson group published in Reproduction shows that a common technique required for in vitro fertilization changes how genes are expressed in the placenta and alters fetal and placental growth with potential implications on life-long health.

Common technique used in IVF impacts placenta growth and function - Read More…

PDN students win prizes for best oral presentation at Anatomical Meetings

The British Association of Clinical Anatomists has awarded prizes to Tabbie Brough and Katie James, while Claudia Santoni has been awarded by the Anatomical Society

PDN students win prizes for best oral presentation at Anatomical Meetings - Read More…

Evidence for an effect of receptor density on ligand occupancy and agonist EC50

In this study in Scientific Reports Gavin Jarvis and co-author Andrew Thompson reveal an unexpected effect on the relationship between drug concentration and effect

Evidence for an effect of receptor density on ligand occupancy and agonist EC50 - Read More…

Cell corners essential for correct development of cell shapes

Cell corners essential for correct development of cell shapes

New study by the Sanson group published in PLoS Biology shows that cell corners are important for normal morphogenesis in epithelia

Cell corners essential for correct development of cell shapes - Read More…

Research in sheep suggests possible early test for fetal heart health

Research in sheep suggests possible early test for fetal heart health

New study led by Dino Giussani shows that changes in heart rate due to hypoxia in advaced pregnancies could be used to predict the future heart health of babies

Research in sheep suggests possible early test for fetal heart health - Read More…

Placenta changes could mean male offspring of older mums more likely to develop heart problems in later life

Placenta changes could mean male offspring of older mums more likely to develop heart problems in later life

Changes occur in the placenta in older pregnant mothers leading to a greater likelihood of poor health in their male offspring, a study in rats by CTR has shown

Placenta changes could mean male offspring of older mums more likely to develop heart problems in later life - Read More…

Dr Paul Schofield awarded Alan Turing Fellowship

Dr Paul Schofield awarded Alan Turing Fellowship

Schofield's work in machine learning has been recognized by the national institute for data science and artificial intelligence

Dr Paul Schofield awarded Alan Turing Fellowship - Read More…

PDN unveils new departmental logo

The new logo was chosen as the winner of an internal competition among its staff

PDN unveils new departmental logo - Read More…

How synapse formation drives brain cancer growth

How synapse formation drives brain cancer growth

A study just published in Nature, by a team including Hugh Robinson of PDN, has shed new light on how glutamate receptor ion channels are involved in metastasis of cancer to the brain, showing that cancer cells which express growth-promoting glutamate receptors integrate themselves into neuronal synapses to obtain activating glutamate.

How synapse formation drives brain cancer growth - Read More…

Potential therapeutic target for early-onset preeclampsia

Potential therapeutic target for early-onset preeclampsia

Research by CTR in collaboration with Andrew Murray identified a protein response pathway during preeclampsia which could provide a new insight for potential therapeutic target of the disease

Potential therapeutic target for early-onset preeclampsia - Read More…

Margherita Turco receives ERC starting grant award

Margherita Turco receives ERC starting grant award

The CTR researchers is among 8 Cambridge recipients of European Union awards given to early-career researchers from over 50 countries

Margherita Turco receives ERC starting grant award - Read More…

Exercise in pregnancy improves health of obese mothers by restoring their tissues

Exercise in pregnancy improves health of obese mothers by restoring their tissues

Exercise immediately prior to and during pregnancy restores key tissues in the body, making them better able to manage blood sugar levels and lowering the risk of long term health problems, suggests new research carried out in mice by CTR

Exercise in pregnancy improves health of obese mothers by restoring their tissues - Read More…

Machine learning tool improves tracking of tiny moving particles

Machine learning tool improves tracking of tiny moving particles

A new automated tool developed by the Franze Lab and driven by machine learning technology may make it easier and faster for scientists to track the movement of tiny particles inside living cells

Machine learning tool improves tracking of tiny moving particles - Read More…

Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation

Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation

New paper by the Zernicka-Goetz group shows that cross-talk between the embryonic epiblast and the extraembryonic trophectoderm orchestrates the transformation of the blastocyst to the egg cylinder

Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation - Read More…

Individual variation in genes alters our ability to regulate emotions

Individual variation in genes alters our ability to regulate emotions

A new study in marmoset monkeys by Dr Andrea M. Santangelo and Prof Angela Roberts, suggests that individual variation in genes alters our ability to regulate emotions, of relevance to our understanding of anxiety and depression, and provides insights for the development of new strategies in individualised therapies

Individual variation in genes alters our ability to regulate emotions - Read More…

Scientists identify possible source of the ‘Uncanny Valley’ in the brain

Scientists identify possible source of the ‘Uncanny Valley’ in the brain

Scientists from Fabian Grabenhorst's group have identified mechanisms in the human brain that could help explain the phenomenon of the ‘Uncanny Valley’ – the unsettling feeling we get from robots and virtual agents that are too human-like. They have also shown that some people respond more adversely to human-like agents than others.

Scientists identify possible source of the ‘Uncanny Valley’ in the brain - Read More…

How the placenta and the fetus engage in regulated communication during pregnancy

How the placenta and the fetus engage in regulated communication during pregnancy

Study by Amanda Sferruzzi-Perri's lab, published in eLIFE, shows how the placenta and the fetus engage in a two-way communication during pregnancy, suggesting that faulty signalling can cause growth restriction

How the placenta and the fetus engage in regulated communication during pregnancy - Read More…

Elisa Galliano awarded teaching prize by CUSU

Elisa Galliano awarded teaching prize by CUSU

The Cambridge University Student Union has given Dr Galliano a prize for best Undergraduate Supervisor (science and tech category) as part of their student-led teaching awards

Elisa Galliano awarded teaching prize by CUSU - Read More…

Dr Cecilia Brassett awarded 2019 Pilkington Prize

Dr Cecilia Brassett awarded 2019 Pilkington Prize

PDN's Clinical Anatomist has been awarded a the Pilkington Prize in recognition of her outstanding contribution to excellent teaching and course development

Dr Cecilia Brassett awarded 2019 Pilkington Prize - Read More…

Amygdala neurons simulate decisions of social partners

Amygdala neurons simulate decisions of social partners

Fabian Grabenhorst and Wolfram Schultz have identified special types of brain cells that may allow us to simulate the decision-making processes of others, thereby reconstructing their state of mind and predicting their intentions. Dysfunction in these ‘simulation neurons’ may help explain difficulties with social interactions in conditions such as autism and social anxiety.

Amygdala neurons simulate decisions of social partners - Read More…

Premature babies could benefit from changes to drugs administered to at-risk mothers

Premature babies could benefit from changes to drugs administered to at-risk mothers

Research by Dino Giussani's group have suggested that subtle changes to the drugs administered to mothers threatened with preterm birth or to premature babies could further improve clinical treatment and help increase their safety

Premature babies could benefit from changes to drugs administered to at-risk mothers - Read More…

CTR members awarded prizes at SRI meeting

CTR members awarded prizes at SRI meeting

Several members of the Centre for Trophoblast research receive prizes during the 66th meeting of the Society for Reproductive Investigation in Paris

CTR members awarded prizes at SRI meeting - Read More…

Cambridge University ranked No 1 for study of anatomy and physiology

Cambridge University ranked No 1 for study of anatomy and physiology

According to the Higher Education Statistics Agency, Cambridge tops the worldwide chart for the subjects of anatomy and physiology, increasing its score from the previous year

Cambridge University ranked No 1 for study of anatomy and physiology - Read More…