skip to content

Department of Physiology, Development and Neuroscience

 
Read more at: New paper highlights stem cell and developmental biology findings.

New paper highlights stem cell and developmental biology findings.

8 January 2025

Congratulations to members of the PDN community, who published a new paper today in Cell Stem Cell, highlighting various findings that are significant for both stem cell and developmental biology. The paper, ‘ Ectopic expression of DNMT3L in human trophoblast stem cells restores features of the placental methylome ’...


Read more at: Congratulations to Professor Kathy Niakan

Congratulations to Professor Kathy Niakan

6 January 2025

A wonderful start to the New Year as we receive news that Professor Kathy Niakan , is winner of the Genetics Society's 2025 Mary Lyon Medal . Named after the distinguished geneticist Mary Lyon FRS, the award was established in 2015 to reward outstanding research in genetics to scientists who are in the middle of their...


Read more at: In Memorium, Professor Roger Thomas

In Memorium, Professor Roger Thomas

17 December 2024

We are saddened by news of the passing of Emeritus Professor of Physiology, Roger Thomas . Roger became Head of Physiology at the University Cambridge in 1996 - having moved from Bristol where he had been both Head of Physiology and Dean of Medical Sciences. He oversaw the merger with Anatomy, and continued as Head of...


Read more at: Funding celebration for PDN lab

Funding celebration for PDN lab

11 November 2024

Prof Katja Röper was recently awarded a Wellcome Discovery Award of more than £3m over 8 years to study ’Supracellular coordination in tissue morphogenesis’. Using the fruit fly and human renal organoids as models, her lab aims to understand how processes are coordinated across the molecular, cell and tissue scale during...


Read more at: Novel strategy for the treatment of neurodegenerative disorders

Novel strategy for the treatment of neurodegenerative disorders

7 November 2024

A new study published by the Fleming lab reveals a novel strategy for treating neurodegenerative disorders. Tauopathies are neurodegenerative diseases which show intracellular accumulation and aggregation of tau protein. In diseases such as Pick's disease, progressive supranuclear palsy, corticobasal degeneration, and...


Read more at: Stockholm International Youth Science Seminar

Stockholm International Youth Science Seminar

23 October 2024

Congratulations to Anna Cochrane, a PhD student in the Giussani Lab, who has been selected by PDN to represent the University of Cambridge at the Stockholm International Youth Science Seminar this year. Anna's selection is based on the quality of her ongoing PhD work, academic achievement, and international conference...


Read more at: Research Culture Celebration

Research Culture Celebration

14 October 2024

Congratulations to Professor Kathy Niakan and Dr Fenzhu Xiong on their nomination for the Research Culture Celebration 2024 , in recognition of their contributions to positive Research Culture among their colleagues. Both were nominated both as an individual PI and Dr Fenzhu Xiong's group was also nominated in the group...


Read more at: AstraZeneca funded studentships

AstraZeneca funded studentships

14 October 2024

Two new AstraZeneca funded studentships, working with the Rawlins and Robinson labs at PDN, and starting Oct 2025 are now accepting applications. AstraZeneca Funded Non Clinical PhD Studentship (Fixed Term) in Ion channels and excitability in neuroendocrine cancer a collaborative project jointly supervised by Prof Hugh...


Read more at: Marmoset Trophoblast Stem Cells Model Shallow Embryo Implantation
Image of a marmoset embryo implanting into the uterus. The embryo (blue, central) expands to fill out the cavity and establishes only superficial contact with the uterus (green)

Marmoset Trophoblast Stem Cells Model Shallow Embryo Implantation

25 September 2024

PDN scientists have developed a pioneering method to culture marmoset placental cells in the lab, offering new insights into embryo implantation. Unlike human embryos, which implant deeply into the uterus, marmoset embryos undergo a much shallower implantation. This research opens new avenues for understanding the...


Read more at: Mother’s gut microbiome during pregnancy shapes baby’s brain development

Mother’s gut microbiome during pregnancy shapes baby’s brain development

21 August 2024

A study in mice has found that the bacteria Bifidobacterium breve in the mother’s gut during pregnancy supports healthy brain development in the fetus. Researchers from the Centre for Trophoblast Research, PDN, have compared the development of the fetal brain in mice whose mothers had no bacteria in their gut, to those...