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Machine learning tool improves tracking of tiny moving particles

Machine learning tool improves tracking of tiny moving particles

A new automated tool developed by the Franze Lab and driven by machine learning technology may make it easier and faster for scientists to track the movement of tiny particles inside living cells

Machine learning tool improves tracking of tiny moving particles - Read More…

Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation

Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation

New paper by the Zernicka-Goetz group shows that cross-talk between the embryonic epiblast and the extraembryonic trophectoderm orchestrates the transformation of the blastocyst to the egg cylinder

Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation - Read More…

Individual variation in genes alters our ability to regulate emotions

Individual variation in genes alters our ability to regulate emotions

A new study in marmoset monkeys by Dr Andrea M. Santangelo and Prof Angela Roberts, suggests that individual variation in genes alters our ability to regulate emotions, of relevance to our understanding of anxiety and depression, and provides insights for the development of new strategies in individualised therapies

Individual variation in genes alters our ability to regulate emotions - Read More…

Scientists identify possible source of the ‘Uncanny Valley’ in the brain

Scientists identify possible source of the ‘Uncanny Valley’ in the brain

Scientists from Fabian Grabenhorst's group have identified mechanisms in the human brain that could help explain the phenomenon of the ‘Uncanny Valley’ – the unsettling feeling we get from robots and virtual agents that are too human-like. They have also shown that some people respond more adversely to human-like agents than others.

Scientists identify possible source of the ‘Uncanny Valley’ in the brain - Read More…

How the placenta and the fetus engage in regulated communication during pregnancy

How the placenta and the fetus engage in regulated communication during pregnancy

Study by Amanda Sferruzzi-Perri's lab, published in eLIFE, shows how the placenta and the fetus engage in a two-way communication during pregnancy, suggesting that faulty signalling can cause growth restriction

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Elisa Galliano awarded teaching prize by CUSU

Elisa Galliano awarded teaching prize by CUSU

The Cambridge University Student Union has given Dr Galliano a prize for best Undergraduate Supervisor (science and tech category) as part of their student-led teaching awards

Elisa Galliano awarded teaching prize by CUSU - Read More…

Dr Cecilia Brassett awarded 2019 Pilkington Prize

Dr Cecilia Brassett awarded 2019 Pilkington Prize

PDN's Clinical Anatomist has been awarded a the Pilkington Prize in recognition of her outstanding contribution to excellent teaching and course development

Dr Cecilia Brassett awarded 2019 Pilkington Prize - Read More…

Amygdala neurons simulate decisions of social partners

Amygdala neurons simulate decisions of social partners

Fabian Grabenhorst and Wolfram Schultz have identified special types of brain cells that may allow us to simulate the decision-making processes of others, thereby reconstructing their state of mind and predicting their intentions. Dysfunction in these ‘simulation neurons’ may help explain difficulties with social interactions in conditions such as autism and social anxiety.

Amygdala neurons simulate decisions of social partners - Read More…

Premature babies could benefit from changes to drugs administered to at-risk mothers

Premature babies could benefit from changes to drugs administered to at-risk mothers

Research by Dino Giussani's group have suggested that subtle changes to the drugs administered to mothers threatened with preterm birth or to premature babies could further improve clinical treatment and help increase their safety

Premature babies could benefit from changes to drugs administered to at-risk mothers - Read More…

CTR members awarded prizes at SRI meeting

CTR members awarded prizes at SRI meeting

Several members of the Centre for Trophoblast research receive prizes during the 66th meeting of the Society for Reproductive Investigation in Paris

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Cambridge University ranked No 1 for study of anatomy and physiology

Cambridge University ranked No 1 for study of anatomy and physiology

According to the Higher Education Statistics Agency, Cambridge tops the worldwide chart for the subjects of anatomy and physiology, increasing its score from the previous year

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Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring

Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring

New research by Christine Holt’s laboratory reveals a cue-induced noncanonical mechanism of translation regulation in axons, which is required for the development of the visual pathway.

Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring - Read More…

Boosting glutamate reduces anxiety in monkeys

Boosting glutamate reduces anxiety in monkeys

New study led by Hannah Clarke, published in JNeurosci, show that increasing levels of the neurotransmitter glutamate in the hippocampus normalizes anxious monkey’s “fight or flight” response

Boosting glutamate reduces anxiety in monkeys - Read More…

Heart disease risk begins in the womb, study in sheep suggests

Heart disease risk begins in the womb, study in sheep suggests

Offspring whose mothers had a complicated pregnancy may be at greater risk of heart disease in later life, according to a new study in sheep by Dino Giussani's lab

Heart disease risk begins in the womb, study in sheep suggests - Read More…

Placentas adapt to help keep babies healthy when mothers have poor diets or low oxygen during pregnancy

Placentas adapt to help keep babies healthy when mothers have poor diets or low oxygen during pregnancy

CTR researchers have discovered the placenta regulates how much oxygen and nutrients it transports to babies during challenging pregnancies in a study using mice to model conditions in the womb

Placentas adapt to help keep babies healthy when mothers have poor diets or low oxygen during pregnancy - Read More…

Former PDN student awarded Anatomical Society Best Image prize

Former PDN student awarded Anatomical Society Best Image prize

Léa Wenger, a former part 2 student, has just been awarded the runner-up prize of the Anatomical Society Best Image competition

Former PDN student awarded Anatomical Society Best Image prize - Read More…

Mechanics paves the way for nerve cells

Mechanics paves the way for nerve cells

By tracking real-time changes in physical properties of the embryonic brain, researchers from the Franze lab have shown that changes in brain stiffness tell growing nerve cells which way to turn

Mechanics paves the way for nerve cells - Read More…

Late endosomes serve as mRNA translation platforms and help to sustain mitochondrial health in axon

Late endosomes serve as mRNA translation platforms and help to sustain mitochondrial health in axon

New research by Christine Holt and colleagues published in Cell shows that late endosomes serve as mRNA translation platforms and help to sustain mitochondrial health in the axons of neurons

Late endosomes serve as mRNA translation platforms and help to sustain mitochondrial health in axon - Read More…

Ewa Paluch receives 2019 Blavatnik Award for Young Scientists in the UK

Ewa Paluch receives 2019 Blavatnik Award for Young Scientists in the UK

Prof Paluch is the 2019 Laureate in Life Sciences and will receive the award and associated cash prize at the March Blavatnik Awards Ceremony to be held at the V&A.

Ewa Paluch receives 2019 Blavatnik Award for Young Scientists in the UK - Read More…

PDN Part II students awarded BACA prize

Two of our Part II PDN students from last year who did anatomy projects with the Human Anatomy Teaching Group have been awarded the prize for best oral presentation at the BACA (British Association of Clinical Anatomists) and Anatomical Society meetings

PDN Part II students awarded BACA prize - Read More…

CTR study on mini placentas makes Guardian 2018 science stories list

CTR study on mini placentas makes Guardian 2018 science stories list

The miniature placenta study by Margherita Turco and her CTR colleagues has been featured in a list of science stories that shook 2018 by The Guardian

CTR study on mini placentas makes Guardian 2018 science stories list - Read More…

Using the marmoset brain to understand depression

Using the marmoset brain to understand depression

Marmoset study by the Roberts lab shows how over-activity in a specific area of the brain’s frontal lobe blunts the anticipatory excitement and motivation for reward – core symptoms of depression.

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Physical forces, not shape, identified as driving factor of cell division direction

Physical forces, not shape, identified as driving factor of cell division direction

Study by the Sanson Lab published in Developmental Cell sheds light on the driving mechanisms that determine the direction of the plane of division during development

Physical forces, not shape, identified as driving factor of cell division direction - Read More…

‘Mini-placentas’ could provide a model for early pregnancy

‘Mini-placentas’ could provide a model for early pregnancy

PDN researchers say that new ‘mini-placentas’ – a cellular model of the early stages of the placenta – could provide a window into early pregnancy and help transform our understanding of reproductive disorders. Details of this new research are published today in the journal Nature.

‘Mini-placentas’ could provide a model for early pregnancy - Read More…

Single-cell reconstruction of the early maternal–fetal interface in humans

Single-cell reconstruction of the early maternal–fetal interface in humans

Transcriptomes of about 70,000 single cells from first-trimester deciduas and placentas reveal subsets of perivascular, stromal and natural killer cells in the decidua, according to new research by CTR published on Nature

Single-cell reconstruction of the early maternal–fetal interface in humans - Read More…

New mechanisms of action for platelet inhibition identified

New mechanisms of action for platelet inhibition identified

Study by Gavin Jarvis on citalopram-induced platelet inhibition reports evidence for two novel and putative mechanisms of inhibition

New mechanisms of action for platelet inhibition identified - Read More…

Predatory flies use "homing missile" system to intercept preys mid-air

Predatory flies use "homing missile" system to intercept preys mid-air

New study by Gonzalez-Bellido lab published on the Journal of the Royal Society Interface sheds light on the underlying system behind predation and navigation in insects

Predatory flies use "homing missile" system to intercept preys mid-air - Read More…

Sequential formation and resolution of multiple rosettes drive embryo remodelling after implantation

Sequential formation and resolution of multiple rosettes drive embryo remodelling after implantation

New study by Magda Zernicka-Goetz's lab on Nature Cell Biology examines the mechanisms of cavity formation during development for the correct formation of the embryo

Sequential formation and resolution of multiple rosettes drive embryo remodelling after implantation - Read More…