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Department of Physiology, Development and Neuroscience

Hippocampal cells encode spatial relations in the environment, including reward locations. In a study published in Current Biology, PDN researchers Prez Jarzebowski, Audrey Hay and Ole Paulsen, with Benjamin Grewe at ETH Zürich, show that memory of reward location is differently encoded along the hippocampus. In dorsal CA1, population activity increases in anticipation of reward but the pool of active cells changes with the reward location. In intermediate CA1, the same cells anticipate multiple reward locations.