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New research published by Giussani/Kane

3 February 2023

dino_giussani_and_andrew_kane_590x488.jpg Combined steroid and statin treatment could reduce ‘accelerated ageing’ in preterm babies, study in rats suggests A new study into new-born rats, which are naturally born prematurely, has combined glucocorticoid steroids and statin therapy. The results, published today in...

Immunofluorescence image of a mouse E12.5 placenta. The red and green fluorescence stain for the two layers of syncytiotrophoblast within the placental labyrinth – the primary site for nutrient exchange between mother and foetus

New paper explores the role of DNA methylation in placental development

24 January 2023

DNA methylation is a repressive epigenetic modification that is essential for development, exemplified by the embryonic and perinatal lethality observed in mice lacking de novo DNA methyltransferases (DNMTs). A new paper characterises the role for DNMT3A, 3B and 3L in gene regulation and development of the mouse placenta...

New studies from the Surani Lab

23 January 2023

Two new studies have been published by the Surani lab . The first, led by Wolfram Gruhn, has discovered that epigenetic resetting in the human germline is associated with profound changes in repressive histone modifications. Gruhn et al. find that the loss of repressive epigenetic information in the early human germline...

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New research published by Giussani/Kane

New paper explores the role of DNA methylation in placental development

New studies from the Surani Lab

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