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Department of Physiology, Development and Neuroscience

 
Read more at: The game of fate: tracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo
The game of fate: tracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo

The game of fate: tracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo

9 May 2018

New paper on Nature Communications by Magda Zernicka Goetz in collaboration with researchers from the University of Nevada digs into one of the central questions of developmental biology, single cell differentiation


Read more at: How muscle satellite-like cells remain undifferentiated
How muscle satellite-like cells remain undifferentiated

How muscle satellite-like cells remain undifferentiated

30 April 2018

New study by Hadi Boukhatmi and Sarah Bray shows population of adult satellite-like cells in Drosophila maintained through a switch in RNA-isoforms


Read more at: Transcription factor HIF2a necessary for the development and function of the carotid body.
Transcription factor HIF2a necessary for the development and function of the carotid body.

Transcription factor HIF2a necessary for the development and function of the carotid body.

30 April 2018

Study by Randall Johnson's lab uses genetic and physiological analysis to demonstrate the essential role of the transcription factor HIF-2alpha in the sympathetic nervous system control of the ventilatory response to hypoxia


Read more at: ‘Sleeping’ stem cells could aid regenerative medicine for brain repair
‘Sleeping’ stem cells could aid regenerative medicine for brain repair

‘Sleeping’ stem cells could aid regenerative medicine for brain repair

9 April 2018

Scientists at the Wellcome Trust/ Cancer Research UK Gurdon Institute, University of Cambridge, have identified a new type of stem cell in the brain which they say has a high potential for repair following brain injury or disease.


Read more at: New studies describe role of glutamate receptor ion channels in cancer progression
New studies describe role of glutamate receptor ion channels in cancer progression

New studies describe role of glutamate receptor ion channels in cancer progression

5 April 2018

Two studies published in Open Biology and Cancer Cell, co-authored by Hugh Robinson, have shed new light on how glutamate receptor ion channels are involved in cancer progression


Read more at: Azim Surani to receive coveted Canada Gairdner International Award for discovery of genomic imprinting
Azim Surani to receive coveted Canada Gairdner International Award for discovery of genomic imprinting

Azim Surani to receive coveted Canada Gairdner International Award for discovery of genomic imprinting

29 March 2018

Azim Surani of the Gurdon Institute and Davor Solter of the Max Planck Institute of Immunobiology and Epigenetics will receive Canada's top research award from the Gairdner Foundation in recognition of their work establishing the field of epigenetics with the discovery of genomic imprinting


Read more at: Study shows how muscles regulate their oxygen consumption
Study shows how muscles regulate their oxygen consumption

Study shows how muscles regulate their oxygen consumption

27 March 2018

A new study by Randall Johnson published in Cell Metabolism shows that an enzyme called FIH determines how muscles consume oxygen. Without the enzyme, the need for oxygen increases during physical exercise. The finding is of potential significance to elite athletes, who have been found to have higher levels of FIH in their muscles than others.


Read more at: The world's highest lab is uncovering the secrets of extreme fitness
The world's highest lab is uncovering the secrets of extreme fitness

The world's highest lab is uncovering the secrets of extreme fitness

21 March 2018

Andrew Murray, part of the Xtreme Everest project, was interviewed by Wired Magazine on the difficulties of testing Sherpas in high altitude, low oxygen environments


Read more at: Dr Matt Mason awarded 2018 Pilkington Prize
Dr Matt Mason awarded 2018 Pilkington Prize

Dr Matt Mason awarded 2018 Pilkington Prize

5 March 2018

The Pilkington Prize award acknowledges excellence in teaching at the University of Cambridge


Read more at: How does the brain’s spatial map change when we change the shape of the room?
How does the brain’s spatial map change when we change the shape of the room?

How does the brain’s spatial map change when we change the shape of the room?

5 March 2018

Study published in Science by Juljia Kupric examines the role of “metric” cells in the GPS of the brain