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Professor Ole Paulsen MD PhD

Professor Ole Paulsen, MD PhD

Principal Investigator

Chair of Physiology (1883)

Fellow St John's College

Ole Paulsen is accepting applications for PhD students.


Office Phone: +44 (0) 1223 333804, Fax: +44 (0) 1223 333840

Research Interests

The primary interest of my group is the relationship between network oscillations and synaptic plasticity. Network oscillations naturally organise spike timing conducive to spike timing-dependent plasticity (STDP), a strong candidate for a mechanism involved in neural development as well as learning and memory processes. We aim to gain insight into how information can be stored and retrieved as changes of synaptic weights in neural networks displaying oscillatory activity. To this end, we use a combination of techniques, including whole-cell patch-clamp and planar multi-electrode recording, calcium imaging and light-activated channels (channelrhodopsins).

More information about my group's research interest can be found at the Neuronal Oscillations Group website.

Plain English

We are interested in how the brain processes information. Our ambition is to elucidate the neural code for memory: how information is encoded, stored and retrieved in a network of neurons. To that end, we study the ability of synapses (the part of the neuron which passes electricity to other neurons) to strengthen or weaken over time, a process called synaptic plasticity.

Neuronal Oscillations Group

Our group is interested in the cellular basis of information processing in the mammalian brain.