Eva Pillai

Exploring the role of mechanics in nervous system development

Neurons in the eye extend axons across massive distances to reach their synaptic target in the brain. Most studies of this process have focused on how chemical molecules guide axon navigation accurately. Our lab has shown that local tissue stiffness in the brain also regulates the pathfinding decisions of these axons.

Hence, in my project, I am studying the interplay between these mechanical and chemical signals during visual system development.

Kristian Franze