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Department of Physiology, Development and Neuroscience

 
Read more at: Common technique used in IVF impacts placenta growth and function
Common technique used in IVF impacts placenta growth and function

Common technique used in IVF impacts placenta growth and function

16 January 2020

New mouse study by the Watson group published in Reproduction shows that a common technique required for in vitro fertilization changes how genes are expressed in the placenta and alters fetal and placental growth with potential implications on life-long health.


Read more at: Placenta changes could mean male offspring of older mums more likely to develop heart problems in later life
Placenta changes could mean male offspring of older mums more likely to develop heart problems in later life

Placenta changes could mean male offspring of older mums more likely to develop heart problems in later life

28 November 2019

Changes occur in the placenta in older pregnant mothers leading to a greater likelihood of poor health in their male offspring, a study in rats by CTR has shown


Read more at: In older pregnancies, males and females have it differently
In older pregnancies, males and females have it differently

In older pregnancies, males and females have it differently

20 November 2019

In a new study in rats, Amanda Sferruzzi-Perri’s lab has identified changes in the placenta that may be responsible for the different health outcomes of offspring caused by advanced maternal age that depend on the sex of the fetus –with males from aged mothers being more susceptible to developing cardiovascular problems in later life, compared to females


Read more at: Margherita Turco receives ERC starting grant award
Margherita Turco receives ERC starting grant award

Margherita Turco receives ERC starting grant award

4 September 2019

The CTR researchers is among 8 Cambridge recipients of European Union awards given to early-career researchers from over 50 countries


Read more at: Exercise in pregnancy improves health of obese mothers by restoring their tissues
Exercise in pregnancy improves health of obese mothers by restoring their tissues

Exercise in pregnancy improves health of obese mothers by restoring their tissues

30 August 2019

Exercise immediately prior to and during pregnancy restores key tissues in the body, making them better able to manage blood sugar levels and lowering the risk of long term health problems, suggests new research carried out in mice by CTR


Read more at: Placentas adapt to help keep babies healthy when mothers have poor diets or low oxygen during pregnancy
Placentas adapt to help keep babies healthy when mothers have poor diets or low oxygen during pregnancy

Placentas adapt to help keep babies healthy when mothers have poor diets or low oxygen during pregnancy

21 January 2019

CTR researchers have discovered the placenta regulates how much oxygen and nutrients it transports to babies during challenging pregnancies in a study using mice to model conditions in the womb


Read more at: CTR study on mini placentas makes Guardian 2018 science stories list
CTR study on mini placentas makes Guardian 2018 science stories list

CTR study on mini placentas makes Guardian 2018 science stories list

8 January 2019

The miniature placenta study by Margherita Turco and her CTR colleagues has been featured in a list of science stories that shook 2018 by The Guardian


Read more at: ‘Mini-placentas’ could provide a model for early pregnancy
‘Mini-placentas’ could provide a model for early pregnancy

‘Mini-placentas’ could provide a model for early pregnancy

29 November 2018

PDN researchers say that new ‘mini-placentas’ – a cellular model of the early stages of the placenta – could provide a window into early pregnancy and help transform our understanding of reproductive disorders. Details of this new research are published today in the journal Nature.


Read more at: Genome editing reveals role of gene important for human embryo development
Genome editing reveals role of gene important for human embryo development

Genome editing reveals role of gene important for human embryo development

21 September 2017

CTR researchers have revealed the role of the OCT4 gene in human embryos in the first few days of development. This is the first time that genome editing has been used to study gene function in human embryos.


Read more at: PDN members awarded prizes at IFPA 2017
PDN members awarded prizes at IFPA 2017

PDN members awarded prizes at IFPA 2017

31 August 2017

Nadejda Capatina, Hannah Yong and Joanna Rakoczy received prizes at the International Federation of Placenta Associations meeting in Manchester