Storer Lab
The digit tip is the only part of the limb that can regenerate in mammals. The key step in this process is the formation of the blastema, a transiently proliferating cell mass that generates the different cell types of the digit to replicate the original structure. Therefore, understanding how the blastema forms and functions during digit tip regeneration will provide clues as to how they can stimulate regeneration of limbs and other tissues.
The Storer Group seeks to understand the cellular and molecular mechanisms necessary for blastema formation, and how these cells are co-ordinated temporally and spatially to regenerate the injured digit tip. Toward that end, they utilise in vitro blastema cultures, single-cell transcriptomic approaches and in vivo genetic lineage tracing studies.
Members
- Mekayla Storer
- Lauren Connolly
- Henry Clay
- Camille Dumas
- Kentaro Hirose
- Sherine Awad Mahmoud
- Isabella Mattimore
- Evelina Sliauteryte
- Eleanor Stephens
- Jia Hua Wang