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Pluripotency regulates mouse and human embryonic morphogenesis: cells that are in an unrestricted naive pluripotent state (marked by the expression of Nanog in yellow) fail to undergo proper morphogenesis and form the amniotic cavity (left structure). Loss of naive pluripotency (marked by the lack of Nanog expression) directs morphogenesis and amniotic cavity formation (right structure). Magenta labels Podocalyxin (luminal protein), cyan labels F-actin (cellular shapes) and blue labels nuclei.
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Brief sensory deprivation triggers cell type-specific structural and functional plasticity in olfactory bulb neurons

Feb 15, 2021

A new study by Elisa Galliano and colleagues in the Grubb lab at King’s College London was recently published in the Journal of Neuroscience. The authors investigated how a short-lived loss of smell (akin to a mild cold) induces functional and structural plasticity in a specific sub-population of dopaminergic interneurons in the mouse olfactory bulb.

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