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Dr Damiano Porcelli

I investigate molecular mechanisms that are at the basis of Hox transcription factor specificity by implementing chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) in Drosophila.

This person is no longer associated with the organization.

Above: Differential DNA binding of Hox transcription factors Ubx and AbdB over a specific genomic region of D. melanogaster, in the presence or not of the Homothorax (Hth) cofactor. DNAseI profiles show regions of accessible chromatin.