skip to content

Department of Physiology, Development and Neuroscience

 
Geometry can provide long-range mechanical guidance for embryogenesis

Paper from Guy Blanchard, Claire Lye, Benedicte Sanson & Jocelyn Etienne makes cover of Plos Computational Biology

Flow patterns predicted by a continuum model of the whole surface of the Drosophila embryo during axis extension (white arrows), generated by anisotropic Myosin-II contractile forces in the germband (ventral green), and in the posterior mid-gut (posterior green). Modelled flow patterns are similar to real cell flows (yellow shell) based on SPIM in toto imaging (magenta shell).

blanchard.png

Reference: http://dx.doi.org/10.1371/journal.pcbi.1005443