BCT
BCT is a text-based, deterministic simulator of the chemotaxis signal transduction pathway in E. coli, originally developed by Dennis Bray, Steve Lay and Bob Bourret. Wherever possible, BCT uses rate constants and concentrations available from published data. Since 1996, Matthew Levin has continued the development work, incorporating robust adaptation of the chemotactic response to the attractant aspartate into the core program, as well as a mechanism, conformational spread, that allows the sensitivity of the response to be enhanced. The current version of the program, BCT 4.4 (released 31/4/05), with updated rate constants and other parameters, for the first time features adaptation to a second attractant serine, which acts independently of aspartate through a different type of receptor.
Click on the symbol
to download the Mac version of BCT 4.4
Output of the program
| Site designed by Matthew Levin. This page updated 13 November 2008. |
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